Attila Gürsoy

Dr. Attila Gürsoy is a professor of computer science in the Department of Computer Science and Engineering. He received his PhD degree from the University of Illinois at Urbana-Champaign in Computer Science in 1994. He was a postdoctoral research associate at the Theoretical and Computational Biophysics Group at Beckman Institute UIUC, contributing to the development of a parallel molecular dynamics program – NAMD. Dr. Gürsoy co-directs the COSBI LAB with Dr. Özlem Keskin (Computational and Systems Biology Lab). His research is in the area of computational and integrative network biology, high performance computing and simulations. He develops fast methods for predicting structural models of protein-protein interactions at genome scale, and methods to relate genomic variations to diseases using network biology approaches. Dr. Gürsoy is a member of Science Academy, Turkey. For more information, please visit his personal page.

Selected Publications

Muratcioglu S, Chavan TS, Freed BC, Jang H, Khavrutskii L, Freed RN, Dyba MA, Stefanisko K, Tarasov SG, Gursoy A, Keskin O, Tarasova NI, Gaponenko V, Nussinov R., GTP- Dependent K-Ras DimerizationStructure. 2015 Jul 7;23(7):1325-35.

Baspinar A, Cukuroglu E, Nussinov R, Keskin O, Gursoy A., PRISM: a web server and repository for prediction of protein-protein interactions and modeling their 3D complexes, Nucleic Acids Res. 2014 Jul;42(Web Server issue):W285-9.

Engin HB, Guney E, Keskin O, Oliva B, Gursoy A., Integrating structure to protein-protein interaction networks that drive metastasis to brain and lung in breast cancer. PLoS One. 2013 Nov 22;8(11).

Engin HB, Keskin O, Nussinov R, Gursoy A., A strategy based on protein-protein interface motifs may help in identifying drug off-targets. J Chem Inf Model. 2012, Aug 27;52(8):2273-86.

Tuncbag N., Gursoy A., Nussinov R., Keskin O., Predicting protein-protein interactions on a proteome scale by matching evolutionary and structural similarities at interfaces using PRISMNature Protocol, 2011 vol. 6 (9) pp. 1341-54.