Ceyda Açılan Ayhan

Dr. Ceyda Acilan Ayhan graduated with honors from Bogaziçi University from the Department of Molecular Biology and Genetics in 2001. She earned her doctoral degree in 2006 at the University of Pittsburgh in the department of Molecular, Cellular and Developmental Biology. She pursued her research interests as a post-doctoral associate at the University of Pittsburgh. In 2008, Dr. Ayhan joined TUBITAK, Genetic Engineering and Biotechnology Institute as a Senior Researcher. She received her Chief Senior position in 2013 and her associate professorship in 2014. Since 2018, she started to work as a faculty member at Koç University, in the School of Medicine. Currently, she conducts projects on the mechanism of action of novel anticancer molecules, epigenetic factors that play a role in overcoming anticancer drug resistance and the underlying causes of segregation defects observed in cancer cells. Her work is supported by TÜBİTAK, FP7 Programme, KUSOM and the Turkish Academy of Sciences (TUBA-GEBIP).


Selected Publications

  • Acilan, C., B. Cevatemre, Z. Adiguzel, D. Karakas, E. Ulukaya, N. Ribeiro, I. Correia, and J.C. Pessoa, 2017, Synthesis, biological characterization and evaluation of molecular mechanisms of novel copper complexes as anticancer agents. Biochimica et biophysica acta, 1861(2): p. 218-234.
  • Yerlikaya, A., E. Okur, A.T. Baykal, C. Acilan, I. Boyaci, and E. Ulukaya, 2015, A proteomic analysis of p53-independent induction of apoptosis by bortezomib in 4T1 breast cancer cell line. Journal of proteomics, 113: p. 315-25.
  • Adiguzel, Z., A.T. Baykal, O. Kacar, V.T. Yilmaz, E. Ulukaya, and C. Acilan, 2014, Biochemical and proteomic analysis of a potential anticancer agent: Palladium(II) Saccharinate complex of terpyridine acting through double strand break formation. Journal of proteome research, 13(11): p. 5240-9.
  • Acilan, C. and W.S. Saunders, 2008, A tale of too many centrosomes. Cell, 134(4): p. 572-5.
  • Acilan, C., D.M. Potter, and W.S. Saunders, 2007, DNA repair pathways involved in anaphase bridge formation. Genes, Chromosomes & Cancer, 46(6): p. 522-31.