Ayşe Derya Cavga

Dr. Ayşe Derya Cavga completed her bachelor’s and master’s studies in Molecular Biology and Genetics in Bilkent University, working on liver cancer in the laboratory of Dr. Mehmet Öztürk. She then completed her Ph.D. studies in the Computational Systems Biology Lab in Koç University, under the supervision of Dr. Özlem Keskin, Dr. Attila Gürsoy, and Dr. Nathan Lack. During her Ph.D., she studied protein-protein interactions, RNA-protein interactions, and gene regulatory effects of transcriptions factors within the contexts of prostate cancer as well as circadian clock. She was a visiting researcher at the National Cancer Institute in the U.S., the British Columbia Cancer Research Centre in Vancouver, and in the ULB Center for Diabetes Research in Brussels. As a postdoctoral researcher, she is now a bioinformatician working mostly on next generation sequence data generated in the laboratories of Dr. Tuğba Bağcı Önder, Dr. Tamer Önder and Dr. Nathan Lack, as well as developing her own project with a multi-omics approach.

Selected Publications

  • Cavga AD, Tardu M, Korkmaz T, Keskin O, Ozturk N, Gursoy A, Kavakli IH. Cryptochrome deletion in p53 mutant mice enhances apoptotic and anti-tumorigenic responses to UV damage at the transcriptome level. Funct Integr Genomics. 2019 Sep;19(5):729-742. doi: 10.1007/s10142-019-00680-5
  • Cavga AD, Karahan N, Keskin O, Gursoy A. Taming Oncogenic Signaling at Protein Interfaces: Challenges and Opportunities. Curr Top Med Chem. 2015;15(20):2005-18. doi: 10.2174/1568026615666150519101956
  • Pooley JR, Rivers CA, Kilcooley MT, Paul SN, Cavga AD, Kershaw YM, Muratcioglu S, Gursoy A, Keskin O, Lightman SL. Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA. PLoS One. 2020 Jan 10;15(1):e0227520. doi: 10.1371/journal.pone.0227520
  • Woo G, Fernandez M, Hsing M, Lack NA, Cavga AD, Cherkasov A. DeepCOP: deep learning-based approach to predict gene regulating effects of small molecules. Bioinformatics. 2020 Feb 1;36(3):813-818. doi: 10.1093/bioinformatics/btz645